Worthington Announcements

(last updated 04/27/22)


Worthington Resumes Attendance at 2022 Global Scientific Conferences

After a long pause caused by the COVID pandemic Worthington is exhibiting at a number of annual scientific meetings.

LAKEWOOD, NJ (March 1, 2022) – Worthington is pleased to announce that after hosting a number of virtual exhibits during the COVID pandemic, they will now be exhibiting at global scientific meetings and conferences on location. These annual meetings will include EB ’22, AACR ‘22, AAI ’22, ISSCR ’22, SFN ’22 and Cell Biology. Please visit the events section of the Worthington website for full details.

“Although we were able to support many societies with our virtual exhibit activities during the pandemic, we are excited to be able to visit with customers and business partners in-person,” said Jim Zacka, vice president at Worthington. “We believe these meetings are an excellent way to follow scientific trends and keep an open line of communications with our core markets and customers.”

In addition, Worthington will be represented at a number of local shows and in- house product fairs. Please contact your local Worthington account representative for ongoing support via email at custservice@worthington- biochem.com.

About Worthington Biochemical Corporation

Founded in 1947, Worthington Biochemical Corporation is an industry leader in the development and production of high-quality purified enzymes, proteins, nucleic acids and cell isolation kits for life science research, diagnostics and biotechnology applications. An ISO9001 Certified, primary manufacturer Worthington meets enzyme requirements from research to large-scale bulk bioprocessing and OEM applications. Worthington Biochemical Corporation is a privately held company, headquartered in Lakewood, NJ and has worldwide distribution through a network of distributors.

For more information, contact: marketing@worthington-biochem.com


Worthington Announces the Availability of the Introduction to Enzymes Instructional Video for a New Generation of Researchers an

New educational animated video details enzyme technology for a variety of life science applications.

LAKEWOOD, NJ (November 8, 2021) – Worthington announced today the release of the Introduction to Enzymes instructional video for a variety of life science STEM applications. As one of the leading enzyme specialty companies with a solid 75-year history, the Worthington name has become synonymous with the term “primary enzyme producer”. Worthington has been publishing technical enzyme and applications educational materials since the 1950s.

“With an emphasis on bench scientists, and students interested in life sciences and STEM studies, we published this animated short video,” said Jim Zacka, vice president at Worthington. “Perfect for beginners, this video shows the basics of enzyme interaction in a simple and understandable animated format.”

In addition to the video, the ‘Introduction to Enzymes’ white paper is available as a free downloadable PDF at the company website. For a copy, go to Worthington-Biochem.com

About Worthington Biochemical Corporation

Founded in 1947, Worthington Biochemical Corporation is an industry leader in the development and production of high-quality purified enzymes, proteins, nucleic acids and cell isolation kits for life science research, diagnostics and biotechnology applications. An ISO9001 Certified, primary manufacturer Worthington meets enzyme requirements from research to large-scale bulk bioprocessing and OEM applications. Worthington Biochemical Corporation is a privately held company, headquartered in Lakewood, NJ and has worldwide distribution through a network of distributors.

For more information, contact: marketing@worthington-biochem.com


Worthington Announces the Availability of the New 2021-2022 Enzyme and Biochemical Digital Catalog

Catalog features new products and updated technical resources.

LAKEWOOD, NJ (January 1, 2021) – Worthington announced today the release of the new 2021 - 2022 Enzyme and Biochemical Digital Catalog for biochemistry, cell biology, molecular biology, neuroscience and bioprocessing applications.

As a specialty life science enzyme company with a solid 75-year history, the Worthington name has become synonymous with the term “primary producer”. New products highlighted in the guide includerecombinant Proteinase K.

“We are proud to release our new digital catalog focusing on cell and molecular biology, tissue dissociation and protein research,” said Jim Zacka, vice president at Worthington. “With COVID restrictions preventing our account representatives from seeing researchers in the lab, this digital format allows us to keep our customers abreast of new developments in our specialty enzyme and related biochemical product lines.”

730 Vassar Ave Lakewood, NJ 08701 800.445.9603 • 732.942.1660 Fax: 800.368.3108 • 732.942.9270 www.Worthington-Biochem.com

About Worthington Biochemical Corporation

Founded in 1947, Worthington Biochemical Corporation is an industry leader in the development and production of high-quality purified enzymes, proteins, nucleic acids and cell isolation kits for life science research, diagnostics and biotechnology applications. An ISO9001 Certified, primary manufacturer Worthington meets enzyme requirements from research to large-scale bulk bioprocessing and OEM applications. Worthington Biochemical Corporation is a privately held company, headquartered in Lakewood, NJ and has worldwide distribution through a network of distributors.

For more information, contact: marketing@worthington-biochem.com


We're Back- Upcoming Meetings and Exhibits

Yes, after the long pause caused by the Covid pandemic Worthington is back planning to exhibit at the following meetings:

DateMeetingLocationBooth
04/02/22 - 04/05/22Experimental Biology (EB'22)Philadelphia, PA527
04/08/22 - 04/13/22Amer Assoc fror Cancer ResearchNew Orleans, LA1959
05/06/22 - 05/10/22Immunology (AAI '22)Portland, OR201
06/15/22 - 06/18/22ISSCR '22 (Int'l Stem Cell Research)San Francisco, CA722
07/24/22 - 07/28/22AACC '22 (Clinical Chemistry)Chicago, IL4226
11/12/22 - 11/16/22Soc Neuroscience (SFN '22)San Diego, CATBD
12/03/22 - 12/07/22ASCB (Cell Biology) 2022Washington DCTBD

Please stop by to discuss your research and see the latest product and technical resources available to assist your research applications. 


New Animated Video and White Paper

Looking to increase your knowledge on how specialty enzymes play an important role in your research? We have two new resources to help you better understand the technical aspects of enzymatic interactions in a variety of applications.


Worthington Covid-19 Update

Worthington Biochemical is operational during the Covid-19 Pandemic. Please see our updates under ‘Announcements’ 

 

 

In these difficult and constantly evolving times caused by the COVID-19 pandemic, it's our mutual responsibility to take care of each other and reduce the risk of viral transmission. At Worthington, our top priorities are always our customers, employees and business partners. We are closely monitoring the situation, ensuring that we take all necessary precautions to keep our employees and their families safe. This includes adhering to recommendations from the CDC, the WHO, and other health and governmental authorities.

 

 

Although many states and cities have evolving business restrictions and shelter-in-place orders, Worthington has been operational throughout these shutdowns as an 'essential business’, a manufacturer and supplier of products for biomedical research, diagnosis and vaccine/bioprocessing applications including potential Covid-19 research and diagnostics.  As such, we continue normal operations and taking all recommended precautions to protect our employees, customers and products.

 

 

We want to keep you informed and will be posting this notice and any updates as announcements on our website.

 

·      We continue utilizing our secure systems and communication capabilities to maximize business continuation and flexibility, and will continue to have some personnel working remotely where feasible. 

·      As the pandemic situation evolves there may be minor delays with customer service order processing and shipment which we will update and advise at the time of order placement. 

·      We remain operational and will keep you updated as the situation continues to evolve. 

·      We remain committed to ensuring the safety, integrity and quality of the of the products, processes and personnel in our continuing operations. 

 

 

As a primary supplier, Worthington products are produced at our ISO9001 Certified facility located within the United States, in Lakewood, New Jersey. We maintain significant final product and raw materials inventory to meet customer requirements for an extended period. Production continues to meet customer’s requirements with on-time delivery. Orders can be placed by fax, email and online at any time, and our customer and technical service representatives will do their best to respond to your inquiries in a timely manner.  Additional product details, technical and application information and references from our Enzyme Manual, Tissue Dissociation Guide and other resources are also available online at Worthington-Biochem.com.

 

 

As always, thank you for your use of Worthington products for your life science research and bioprocessing needs. We will continue to work together to assist customers worldwide in advancing research and producing products to aid in combating diseases such as COVID-19 and others. We are here if any additional questions, concerns or comments exist, please let us know.

 

 

Stay safe and healthy!


Worthington Covid-19 Update

 

Worthington Biochemical is operational during the Covid-19 Pandemic. Please see our updates under ‘Announcements’ 

 

 


Worthington Announces the Availability of the 18th Edition Tissue Dissociation Guide for a New Generation of Life Science Resear

New technical education guide includes new applications table, updated references, expanded tissue tables and eye-catching technical wall poster available in print and digital formats.

Worthington announced the release of the 18th edition of the Tissues Dissociation Guide for biochemistry, cell biology, molecular biology, pre-clinical research and bioprocessing applications. As an enzyme specialty company with a solid 70-year history, the Worthington

name has become synonymous with the term “primary enzyme producer”. Worthington has been publishing technical enzyme and applications manuals since the 1950s. “With an emphasis on bench scientists, and students interested in life science and STEM studies, we continually update and create free technical materials from our extensive citations library,” said Jim Zacka, vice president at Worthington. “This manual also includes a pullout wall poster

entitled Exploring the Depths of Cell Isolation, an easy-to-use primary cell isolation enzyme digestion scale for troubleshooting a dissociation and planning isolation strategy.”


USDA TRACES Certification

Worthington Biochemical is pleased to announce that it has renewed approval by the USDA APHIS TRACES to ship intermediate products to the European Union accompanied by the Regulation (EU) 142/2011 Chapter 20 'Declaration for the Import From Third Countries and for the Transit Through the EU of Intermediate Products to be used for the Manufacture of Medicinal Products, Veterinary Products. Medical devices for Medical and Veterinary Purposes, Active Implantable Medical Devices, In Vitro Diagnostics Medical Devices for Medicinal and Veterinary Purposes, Laboratory Reagents and Cosmetic Products", signed by the importer.

As a result, Worthington can export product throughout the EU with proper USDA documentation to meet the growing needs of the life science community worldwide.  Please contact us for additional information.


Worthington Publishes 2019-20 Product Guide & Price List

2019-20 Price List of Enzymes, Biochemicals and Primary Cell Isolation Kits

 

Worthington announced the release of their 2019-20 product guide and price list filled with an extensive product offering for scientific researchers across the globe. New and existing products are included for applications such as Primary Cell Isolation and Cell Culture, Protein Sequencing, Enzymology and Molecular Biology. 

With an ongoing focus on new products, this new Worthington catalog include new higher activities Collagenase Types 6 and 7, Animal Free (AF) STEMxyme® Collagenase/Neutral Protease (Dispase®) Blends, Collagenases, DNase, RNase T2 and other enzymes for regenerative medicine, biopharma and vaccine production applications. 

 Scientists can access the new catalog and product guide in multiple ways:

       Printed Version – Request a printed copy of the catalog  online.:   
http://www.worthington-biochem.com/mailinglist/request.php

       Digital Version – Visit to view the digital version of the catalog 


ISO Recertification Completed

Worthington is proud to announce our successful company-wide ISO9001:2015 recertification upon completion of the three year reassessment audit by ANAB-accredited SGS US Testing Company, Systems & Services Certification on 5/4/18.

Worthington Biochemical develops and produces high quality purified enzymes, proteins, nucleic acids and cell isolation kits for applications in life science research, diagnostics, bioprocessing, biopharm & biotechnology. Founded in 1947 and privately held, Worthington has maintained a reputation for quality products and excellent customer service which their ISO9001:2008 recertification confirms.

With worldwide distribution, Worthington markets products direct to domestic customers and internationally through a network of distributors. Products are supplied for primary cell isolation & cell culture, protein research, molecular biology and many other research applications. As a primary manufacturer, Worthington can meet enzyme requirements from research-scale to bulk bioprocessing quantities with all manufacturing taking place at their facility located in Lakewood, NJ. 

For additional information: Ph: 800.445.9603 • 732.942.0660, Fax: 800.368.3108, 732.942.9270 or visit www.worthington-biochem.com.

Contact: Jim Zacka, VP, ph: 732.942.1660, e-mail: jzacka@worthington-biochem.com


New Products Update

Worthington is pleased to introduce the following new products now produced by Worthington:

STEMxyme® 1 & 2 Collagenase/Neutral Protease (Dispase) Blends, Animal Free, for stem and primary cell isolation applications

Animal Free Collagenase Types AFA, AFB and AFC, also available 0.22u filtered in 50mg vials for convenience

• Collagenase Types 5, 6 & 7 containing higer collagenase and caseinase specific activities  

LowEndo™ Ovalbumin, ≥95% Purity, ≤1Endo U/mg

Endo-Arg-C (Clostripain), Sequencing Grade

Myoglobin, Bovine muscle

• Ribonuclease T2, Recombinant, Animal Origin Free, Purified 

See our updated product catalog listings for additional information on these and all Worthington products. 


NEW! Animal Free Collagenase Grades Available!

Researchers interested in regenerative tissue applications and/or avoiding potential viral and prion risks from commonly used animal sourced fermentation media components now have Animal Free (AF) Collagenases produced by Worthington.

Types AFA, AFB ands AFC collagenase are derived from cultures grown in medium completely devoid of animal based components and designed for bioprocessing applications where introduction of potential animal derived pathogens must be prevented is now available from Worthington. Levels of secondary proteases are similar to Types 1 and 2 collagenase.

These new AF types are also available 0.22 micron filtered and lyophilized in 50mg vials for single use convenience.

Several lots of AF Collagenases are now available for sampling and evaluation in your specific application(s). Please contact Technical Service at 800.445.9603, e-mail: techservice@worthington-biochem.com or request samples on-line, Collagenase Sampling Program.

For more information.


Animal Free Recombinant (AF) DNase I Available!

Bovine pancreatic deoxyribonuclease I produced recombinantly in yeast, Pichia pastoris, to decrease levels of contaminating RNase and eliminate potential pathogens associated with animal based materials is now produced by Worthington.

Bovine pancreas is a rich source of RNase A which is often found in many commercial DNase preparations. Producing DNase I by recombinant means in an organism with much lower levels of endogenous RNase greatly facilitates purification of an enzyme with undetectable levels of RNase. The processes involved in the production and isolation of recombinant DNase I are completely devoid of animal based components which eliminates the possibility of introducing animal derived pathogens into bioprocessing procedures.

Recombinant DNase I is suitable for such applications as:
• Removing genomic DNA from RNA preparations prior to RT-PCR
• Degradation of DNA templates after transcription reactions
• Removing unwanted DNA from samples prior to Northern blotting
• Removing DNA during biopharma and bioprocessing procedures

For more information.


Celase® GMP Collagenase Blend Available

Worthington Launches Celase® GMP an Avian and Mammalian Tissue-free Collagenase and Neutral Protease Enzyme Blend Produced Under GMP Guidelines

New enzyme grade is now available for use in a wide range of applications from initial animal research through clinical trials.

LAKEWOOD, NJ (April 5, 2016) – Worthington announced today at the Experimental Biology Conference in San Diego, the launch of the new Celase® GMP Enzyme product offering. Manufactured by Cytori Therapeutics, this product line is ideal for cell isolation studies for laboratories looking to facilitate a smooth transition from bench and animal research to downstream clinical applications. 

Celase® GMP is a proprietary enzyme containing a unique blend of collagenase, neutral protease and buffer salts that are produced using avian and mammalian tissue-free raw materials, aseptically processed, sterile filtered and highly purified under GMP guidelines. A single, sterile, ready to use enzyme containing both collagenase and a neutral protease is ideal for a wide range of adipose stem cell, biomedical and bioprocessing applications.

This new Celase® GMP product offering is a cost-effective option for laboratories looking for a high-quality GMP enzyme to support their pre-clinical research,” said James Zacka, vice president at Worthington.  “We believe the sooner a researcher recognize a potential for a clinical application it is to their long term regulatory benefit to qualify and use a GMP or equivalent grade of enzyme”

Not all research applications required the use a GMP grade enzyme in early phase studies. However, the recent FDA guidance issued for tissue and cell products specifically cite that GMP grade reagents should be used in drug-type validated processes. Subsequently, both regenerative medicine researchers and clinicians are now looking for GMP quality products with a smoother regulatory approval process as the goal. 

 “The Cytori Celase® Enzyme is currently used in US FDA approved clinical trials. We are excited to offer   a foundational and versatile enzyme for advancing adipose-based research programs from pre-clinical to clinical levels while eliminating the need to perform costly and time consuming bridging studies,” said Jason Streeter, quality engineer at Worthington.

About Worthington Biochemical Corporation
Founded in 1947, Worthington Biochemical Corporation is an industry leader in the development and production of high quality purified enzymes, proteins, nucleic acids and cell isolation kits for life science research, diagnostics and biotechnology applications.  An ISO9001 Certified, primary manufacturer Worthington meets enzyme requirements from research to scale-up bulk bioprocessing and OEM applications. Worthington Biochemical Corporation is a privately held company, headquartered in Lakewood, NJ and has worldwide distribution through a network of distributors.

 


Visit Worthington at Experimental Biology 2016

Worthington Biochemical will be exhibiting at the upcoming Experimental Biology annual meeting next week in San Diego, 4/2-4. Visit booth 921 to learn more about Worthington enzymes for life science research applications including Collagenases, animal free STEMxymes® and Celase® GMP Blends for primary and stem cell isolation, DNases, RNases, and many more. Participate in our survey for a chance to win a new iPad and pick up our latest product information.


Celase® Distribution Agreement

Worthington Biochemical Corporation Announces Expansion of GMP Compliant Enzyme Offering via Strategic Agreement with Cytori Therapeutics

Worthington Biochemical Corporation Signs a Non-exclusive, 3 Year Distribution Agreement for Cytori Celase® GMP Enzymes

LAKEWOOD, NJ (November 30, 2015) – Worthington announced today distribution rights to the Celase® GMP compliant enzyme from Cytori Therapeutics, San Diego, CA. The new Celase® GMP product offering allows Worthington customers focused on cell isolation studies to facilitate a smooth transition from bench and animal research to downstream clinical applications. 

Celase® GMP is a proprietary enzyme containing a unique blend of collagenase, neutral protease and buffer salts that are produced using avian and mammalian tissue-free raw materials, aseptically processed, sterile filtered and highly purified under GMP guidelines. A single, sterile, ready to use enzyme containing both collagenase and a neutral protease is ideal for a wide range of adipose stem cell, biomedical and bioprocessing applications. 

We are excited to offer Cytori’s Celase® GMP product to Worthington’s Collagenase and STEMxyme® portfolio for biomedical research and related bioprocessing applications. It was very important for us to find an enzyme that meets our stringent requirements for high quality and reproducible performance,” said Von Worthington, President and CEO at Worthington Biochemical Corporation.  “This new Celase® GMP product offering will be marketed through our catalog, direct sales force, distributor network, e-commerce website and upcoming scientific meetings.”

Cytori Therapeutics’ extensive product development expertise yields a best-in-class enzyme formulation providing researchers with superior and unparalleled convenience in their lab, clarity in their approach, and confidence in their results.

“We are very excited and pleased to initiate a partnership for Celase® GMP with a respected enzyme manufactured like Worthington which has decades of experience successfully serving the biomedical research and technology field,” said Russ Havranek, Director of Marketing at Cytori Therapeutics.

About Worthington Biochemical Corporation
Founded in 1947, Worthington Biochemical Corporation is an industry leader in the development and production of high quality purified enzymes, proteins, nucleic acids and cell isolation kits for life science research, diagnostics and biotechnology applications.  An ISO9001 Certified, primary manufacturer Worthington meets enzyme requirements from research to scale-up bulk bioprocessing and OEM applications. Worthington Biochemical Corporation is a privately held company, headquartered in Lakewood, NJ and has worldwide distribution through a network of exclusive distributors.
 

About Cytori Therapeutics

Cytori Therapeutics is a late stage cell therapy company developing autologous cell therapies from adipose tissue to treat a variety of medical conditions.  Data from preclinical studies and clinical trials suggest that Cytori Cell Therapy™ acts principally by improving blood flow, modulating the immune system, and facilitating wound repair.  As a result, Cytori Cell Therapy™ may provide benefits across multiple disease states and can be made available to the physician and patient at the point-of-care through Cytori’s proprietary technologies and products.  For more information visit www.cytori.com


Neuroscience Survey Winner

Thomas Shapaker of the University of Tennessee Health Sciences Center is the winner of the Worthington iPAD for participating in the 2015 Neuroscience (SFN) annual meeting neural cell isolation survey held in Chicaho, IL. Congratulations to Thomas and thanks to all survey participants!

Be sure to watch for additional Worthington surveys and contests at upcoming meetings and exhibits.


New Improved Product Labeling

Please be advised that Worthington Biochemical will be implementing new and improved product labeling which will also be in compliance with OSHA’s Hazard Communication Standard, 29CFR 1910.1200 (HCS) to align with the UN Globally Harmonized System of Classification and Labeling of Chemicals (GHS).

Worthington’s new label format will include all of the previous product label information in addition to the potential hazard requirements specified by the OSHA and GHS standards. 

This change is being implemented as a result of new OSHA and GHS standards and our ongoing continuous product and packaging improvement efforts. There will be no changes to existing products, processes or other packaging components.

Products with the new labeling will begin shipping this month and be fully implemented by June 1, 2015, as required by the GHS and OSHA regulations.  Please contact your Sales Representative or Worthington Customer or Technical Service if any additional information is required. 

 Thank you for your continued use of Worthington products. We also welcome your comments or feedback relative to these changes or any Worthington products.


GEN Basic Primary Cell Isolation Article

Genetic Enginerring News (GEN) has published an article from Worthington about Basic Cell Isolation, available at:

 http://www.genengnews.com/insight-and-intelligence/basic-primary-cell-isolation-for-nonperfusion-culture/77900296/


NEW Primary Cell Isolation & Tissue Dissociation Guide Available

Worthington's latest 12th edition Tissue Dissociation Guide is available to assist researchers with selecting enzymes, developing and optimizing protocols and better understanding the process of enzymatic primary cell isolation and tissue dissociation.

The guide also discusses the enzymes most commonly used, their handling and specificity, and includes hundreds of new detailed cell and species-specific references. Available online at www.tissuedissociation.com
Request a copy online, by phone (800.445.9603 or 732.942.1660), or by Fax (732.942.9270).


Tissue Dissociation Guide Now Available on iTunes

Worthington's current edition of the Tissue Dissociation Guide is now available as an ebook on iTunes, https://itunes.apple.com/us/book/tissue-dissociation-guide/id878827138?ls=1&mt=13

 This guide summarizes our knowledge of how enzymes accomplish "routine" operations of tissue dissociation and cell harvesting. Additionally, it describes standard lab procedures, offers a logical experimental approach for establishing a cell isolation protocol, and lists many tissue specific references. 

Requirements: This book was designed for iPad and some features may not work as intended with a mouse or trackpad. To view this book on an iPad, you must have iBooks 3 or later and iOS 5.1 or later. 


Online Customer Satisfaction Survey Now Available

Worthington now has a brief online Customer Satisfaction Survey available for customers to provide feedback and comments about our products and service.

 

We invite you to complete our short Customer Satisfaction Survey  


Isolation of Human Atrial Myocytes for Simultaneous Measurements

Worthington is pleased to have sponsored the video publication of the following:

 Isolation of Human Atrial Myocytes for Simultaneous Measurements of Ca2+Transients and Membrane Currents, Voigt, N., Zhou, X. B., Dobrev, D., J. Vis. Exp. (), e50235, doi:10.3791/50235 (2013).

Short Abstract

We describe the isolation of human atrial myocytes which can be used for intracellular Ca2+ measurements in combination with electrophysiological patch-clamp studies. 

·       http://www.jove.com/video/50235/isolation-human-atrial-myocytes-for-simultaneous-measurements-ca2

·        http://www.jove.com/video/50235

 


Collagenase Product(s) Raw Material Certification

Although it does not affect the majority of research customers, please be aware that the FDA has recently issued a 'Risk of BSE in Collagenase Enzymes' notice to all FDA-regulated users of Collagenases. (5/23/07 FDA Collagenase Note: PDF Version) Worthington currently provides Collagenase to many such customers for which this issue is likely to arise. We recently drafted a document (Collagenase Products Raw Material Certification) in response to the FDA's letter to all regulated Collagenase user, available on our website. Please note that although Worthington is not currently a cGMP manufacturer of collagenase we operate under GMP guidelines and are ISO9001:2000 Certified. In addition and most importantly, Worthington has never used Brain Heart Infusion (BHI) media in our collagenase production process. Other low-risk animal sourced raw materials are of USDA or equivalent inspected and approved as suitable for human consumption. We have also been working on developing a completely Animal Origin Free (AOF) collagenase product and have raised the priority of this due to recent inquiries such as this. We hope to have AOF Collagenase evaluation material available for sampling within a few months. We would welcome the opportunity to provide evaluation samples as soon as they become available if interested. Please let us know if we can be of additional assistance or if any additional information is required by any of your customers. We look forward to continuing to provide collagenase to meet the technical and regulatory requirements of the market.


HEPATOCYTE ISOLATION SYSTEM AVAILABLE!

Optimized and Functionally Tested Enzyme System For Hepatocyte Isolation
The Worthington Hepatocyte Isolation System has been developed to provide researchers with a reliable, convenient, and consistent hepatocyte cell isolation system. By using the pre-optimized combination of enzymes contained in this kit, it is possible to minimize the lot-to-lot variation and improve the quality of the isolated hepatocytes.

In addition, Worthington use-tests each lot by isolating hepatocytes from adult rat to assure performance, reliability, and consistent yield of viable cells. Each kit includes single-use enzyme vials, balanced salt solution, buffer, culture media and an optimized protocol for five separate adult rat liver perfusions. The method is based on that described by Berry, M.N., modified by Seglen, P.O., and further optimized in conjunction with several collaborating researchers.

Available on-line at www.worthington-biochem.com, e-mail: techservice@worthington-biochem.com , Call: 800.445.9603/732.942.1660 or Fax: 732-942-9270 for additional information!


Collagenase Lot Selection Tool Available Online!

Worthington's 'Collagenase Lot Selection Tool' is available online at our website. This new feature was designed to help researchers select and evaluate current collagenase lots that match previous lots or desired activity profiles. Users may enter target values for collagenase, caseinase, clostripan, and tryptic activities or specify previous lot numbers.

Each value can be weighted based on the relative level of importance to the application. After the search for matches is completed, a ranked list of collagenase lots currently available is generated. The selected lots can then be sampled simply by using the built in link to the Free Collagenase Sampling Program.

As always, Worthington Customer and Technical Service personnel are available via phone at 800.445.9603/732.942.1660 and e-mail to assist with collagenase or any other products.